You probably know that Monday, Jan. 19 is a federal holiday -- Martin Luther King Jr. Day. But Tuesday, Jan. 20 is Inauguration Day, and a holiday for some federal employees who work in the District of Columbia. This can affect grant applicants.
Bottom line: The NIH eRA help desk will be closed Tuesday because the staff won't be able to make their way through the inaugural crowds to get to the office. However, if you are submitting a proposal from the comfort of your office, Inauguration Day isn't a holiday for you. It still counts as one of the two "viewing days" of your proposal after submission to the commons. If you submit on Friday, you have until midnight Wednesday to view the proposal.